Effects of minimally invasive removal of intracranial hematoma on blood-brain barrier index and prognosis / 中华老年医学杂志
Chinese Journal of Geriatrics
;
(12): 31-33, 2011.
Article
Dans Chinois
| WPRIM
| ID: wpr-384421
ABSTRACT
Objective To explore the effects of minimally invasive removal of intracranial hematoma on blood-brain barrier (BBB) index, serum myelin basic protein (MBP) and activity of daily living (ADL) in hypertensive patients with cerebral hemorrhage.Methods Through observing 30cases operated within 3.0 hours, 32 case operated between 3. 1-8. 0 hours, 28 cases operated between 8. 1 to 24.0 hours and 22 cases operated over 24 hours, the changes of BBB index, serum MBP and ADL were analyzed. Results The BBB index and serum MBP were significantly lower in patients operated within 8. 0 hours than in patients operated over 8. 1 hours [≤3.0 hours group(6.57±0.69)×10-3 and (3. 12±0.40)μg/L;3. 1-8.0 hours group (7. 37±1.29)×10-3 and (3.25±0.60)μg/L;8. 1-2.0 hours group ( 12. 02± 1.51 ) × 10 3 and (4. 60±0. 48)μg/L;over 24.0 hours group ( 14. 68±2.07)×10-3 and (5.88±0.64)μg/L,Q>13.8,P<0. 05]. And the ADL was lower in patients operated within 8. 0 hours than in patients operated over 8. 1 hours [≤3.0 hours group (2. 60± 1.07)scores; 3.1-8.0 hours group (3. 06±0. 91 )scores;8. 1-24.0 hours group (4.00±0.67) scores;over 24.0 hours group(3.68±1.32)scores,Q>3. 1,P<0.05].Conclusions The minimally invasive surgery of intracranial hematoma within 8.0 hours can mitigate the cytotoxicity-damaged BBB so as to lighten brain edema and improve the patients quality of life.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Type d'étude:
Étude pronostique
langue:
Chinois
Texte intégral:
Chinese Journal of Geriatrics
Année:
2011
Type:
Article
Documents relatifs à ce sujet
MEDLINE
...
LILACS
LIS