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Influence of different anesthesia methods on postoperative changes in T-lymphocyte subsets and cytokines in the patients under want operation of stomach carcinoma / 中国基层医药
Chinese Journal of Primary Medicine and Pharmacy ; (12): 2889-2891, 2010.
Article Dans Chinois | WPRIM | ID: wpr-384956
ABSTRACT
Objective To study the effects of different anesthesia methods on postoperative changes in T-lymphocyte subsets and IL-6IL-10、TNF-α in the patients undergoing operation of stomach carcinoma.Methods 60 patients with stomach carcinoma were randomly divided into group I(general anaesthesia)and Ⅱ(general combined epidural anesthesia).The level of T-lymphocyte subsets and IL-6IL-10、TNF-αt were respectively detected and compared before anesthesia,2 h after anesthesia,ld and 6 d after operation.Results CD3+ 、CD4+ 、CD4+/CD3+ decreased,but IL-6 increased at the end of 2 h after anesthesia,l d after operation compared with those before anesthesia(all P<0.05).While IL-10、TNF-α had no statistical significance(all P>0.05).At 6 d after operation,the values recovered to the level before anesthesia in two groups.Conclusion The immune function in patients with gastric cancer decreaseed after anesthesia,it was more serious in geteral anaesthesia than that of general combined epidural anesthesia.But anesthesia had little influence on inflammatory response.

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) langue: Chinois Texte intégral: Chinese Journal of Primary Medicine and Pharmacy Année: 2010 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) langue: Chinois Texte intégral: Chinese Journal of Primary Medicine and Pharmacy Année: 2010 Type: Article