Progress in study on local mechanism of mechanical loading stimulated osteogenesis / 国际生物医学工程杂志

ABSTRACT

Mechanical loading plays an important role in stimulating osteogenesis. Increasing mechani-cal loading, via sports and mechanical vibration may increase bone mass and imluce better microstructure, where-as, lack of mechanical loading in the situation like space walking, long bed-ridden, ete, results in bone loss and osteoporosis. Although the mechanism through which mechanical loading stimulates bone formation is not clear, experiments have proved that local mechanism is more important than systematic mechanism. This article aims to review the local mechanism of mechanical loading stimulating osteogenesis.