Loss of RASAL1:a new mechanism of ras activation in cancers / 国际肿瘤学杂志
Journal of International Oncology
;
(12): 809-811, 2009.
Article
Dans Chinois
| WPRIM
| ID: wpr-390991
ABSTRACT
Ras is a kind of protein closely related to neoplasms,the persistent activation of which would induce tumorigenesis and progression.RASAL1 is a Ca~(2+) regulated ras GTPase-activating-like protein, the loss or decreased expression of RASAL1 induces ras activation, then results in tumongenesis and progression.In this review we sum up the mechanism of ras activation, the relationship between neoplasms and RASAL1 and the mechanism of RASAL1 expression decreasing.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Journal of International Oncology
Année:
2009
Type:
Article
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