Advances in the pathogenesis of primary intrahepatic cholelithiasis / 中华肝胆外科杂志

ABSTRACT

Primary intrahepatic stone is a common disease in China. It is difficult to treat this benign biliary tract disease because it has many complications and the surgery is difficult. Understanding the cause of this disease has important implications in prevention and treatment. This article reviewed the cause of primary intrahepatic stone from four aspects imbalance of bile components, infection, bile protein, and macromolecular and metabolism of the cells.