The biological characteristics of p300/CBP-associated factor and relationship with disease / 国际儿科学杂志

ABSTRACT

p300/CBP-associated factor (PCAF)is an important histone acetyltransferase in eukaryotic cells. PCAF can acetylizes histone and non-histone. PCAF participates in various biological processes of cells and in the interaction between virus and cells. The imbalance of PCAF would lead to abnormal development of various organs, and related to the development of some tumors.