Effects of Danhong mixture on platelet aggregation of rabbits / 国际中医中药杂志
International Journal of Traditional Chinese Medicine
;
(6): 214-216, 2012.
Article
Dans Chinois
| WPRIM
| ID: wpr-418514
ABSTRACT
Objective To study the effects of Danhong mixture on platelet aggregation of rabbits.Methods 40 rabbits were randomly divided into 5 groups,8 rabbits in each group,of blank control group (treated with 0.5% sodium carboxy methyl cellulose of the same volume),Danhong mixture of 5,2.5,1.25 g/kg group,aspirin group (treated with 0.025 g/kg aspirin).Each group was performed gastric lavage according to the ration of lml/kg,once daily,for continuous 8 days.Blood was obtained from heart 1 hour after last administration,then adenosine diphosphate (ADP),collagen,arachidonic acid (AA) were used for platelet aggregation test.Results Inhibition rate of Danhong mixture (5,2.5,1.25 g/kg) on ADP induced rabbit platelet aggregation were 9.4%,5.1%,and 0.6% respectively,on collagen induced platelet aggregation were 34.5%,11.1%,and 5.6%; on AA induced platelet aggregation were 21.4%,11.6%,and 2.3% respectively.Conclusion Danhong mixture had inhibitive action on platelet aggregation.
Texte intégral:
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Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
International Journal of Traditional Chinese Medicine
Année:
2012
Type:
Article
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