Endothelin-1 and cerebral vasospasm after subarachnoid hemorrhage / 国际脑血管病杂志

ABSTRACT

Cerebral vasospasm (CVS) is a serious complication of aneurysmal subarachnoid hemorrhage (SAH).Endothelin-1 (ET-1) is an endothelium-derived vasoconstrictor substance.A large number of clinical and basic studies have shown that cerebrospinal fluid and/or ET-1 levels in peripheral blood increases in patients with SAH and play an important role in the occurrence and development of CVS.This article reviews the research status of the role of ET-1 in the occurrence and development of CVS.