Early diagnosis of undiscovered nodosity metastasis by hepatic artery Doppler flow imaging perfusion index and contrast-enhanced ultrasound / 中华超声影像学杂志

ABSTRACT

ObjectiveTo investigate the diagnostic value of early undiscovered nodosity metastasis by hepatic artery Doppler flow imaging perfusion index(DPI) and contrast-enhanced ultrasound (CEUS).MethodsSix hundred and fifty-five patients were collected who suffered with malignant tumor which is not from liver and without liver metastasis.DPI were detected in all patients first,and then patients of higher DPI were taken CEUS and contrast-enhanced CT(CECT).All the diagnosis were confirmed by operation,biopsy under ultrasound or follow-up.ResultsAfter 6 months' follow-up,there were 19 patients found liver metastasis in 562 patients without increase of DPI,and 75 patients found liver metastasis in 93 patients with increase of DPI(DPI＞30％).The negative and the positive predictive value were respectively 96.6％and 80.6％.Seventy-five patients were found 132 liver metastasis who were given CEUS,and 60 patients were found 94 liver metastasis who were given CECT,there was significance difference between them( P ＜0.01).ConclusionsThe combination of DPI and CEUS can get higher detection rate of liver metastasis.