Surveillance of Hantaan virus serology in Rattus Novergicus rodent in Thanh Hoa province, 2003

ABSTRACT

Hantaan virus is the pathogene of 2 forms of high mortality of hemorrhagic fever with kidney syndrome and lung syndrome. By using the 4 techniques of enzyme addhesion ELISA, immue fluorescemce, and western blot, 61 samply of serum of Rattus Novergicus, in Thanh Hoa, year 2003, ELISA rat serum was (+) and 9/61 were suspected. More over, by immunofluoresceime and western blot, antihantavirus antibody was confirmed on 6/9 samples. These 6 sample from the rats, were studied by WB technique with specific serum SEO, in 2 samples, 51 KDa band was found. Results concluded that in Rattus Novergicus from Thanh Hoa, anti Hantaan virus antibody was detected.