Phospholipase A2 and Cancer / 国际肿瘤学杂志

ABSTRACT

Phospholipase A2 (PLA2) is consisted of a large group of enzymes,which can hydrolyze Sn-2 ester bond of the phospholipids and have different structures and functions.According to the latest related researches,many subtypes of PLA2 express abnormally in a various of tumors and have a close relationship with cancer proliferation,apoptosis,invasion,metastasis and prognosis.Different subtypes have different effects on neoplasms.PLA2 can supply a new insight on cancer therapy.