Hepatokines as a Link between Obesity and Cardiovascular Diseases
Diabetes & Metabolism Journal
;
: 10-15, 2015.
Article
Dans Anglais
| WPRIM
| ID: wpr-42465
ABSTRACT
Non-alcoholic fatty liver disease, which is considered a hepatic manifestation of metabolic syndrome, independently increases the risks of developing cardiovascular disease (CVD) and type 2 diabetes mellitus. Recent emerging evidence suggests that a group of predominantly liver-derived proteins called hepatokines directly affect the progression of atherosclerosis by modulating endothelial dysfunction and infiltration of inflammatory cells into vessel walls. Here, we summarize the role of the representative hepatokines fibroblast growth factor 21, fetuin-A, and selenoprotein P in the progression of CVD.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Maladies cardiovasculaires
/
Diabète de type 2
/
Athérosclérose
/
Sélénoprotéine P
/
Stéatose hépatique
/
Alpha-2-HS-glycoprotéine
/
Facteurs de croissance fibroblastique
/
Obésité
langue:
Anglais
Texte intégral:
Diabetes & Metabolism Journal
Année:
2015
Type:
Article
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