The Contingent Negative Variation in Remitted Paediatric Bipolar Patients: No Evidence of Abnormality
Psychiatry Investigation
;
: 196-199, 2013.
Article
Dans Anglais
| WPRIM
| ID: wpr-42587
ABSTRACT
Although the Contingent Negative Variation (CNV) paradigm has been useful in schizophrenia, limited research involving such paradigm in subjects with Bipolar Disorder (BD) has produced contradictory findings. To the best of our knowledge, no study has investigated CNV in Paediatric Bipolar Disorder (PBD) subjects. Thirty remitted PBD patients and thirty matched healthy control group subjects participated in the study. No significant between group main effect could be found for either CNV latency or amplitude. We propose that CNV is unlikely to be a true endophenotype of BD. However, absence of CNV finding during euthymic phase in BD may help us in advancing our understanding of BD and such finding may, in fact, have some specificity with regard to differentiating BD from schizophrenia.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Schizophrénie
/
Trouble bipolaire
/
Sensibilité et spécificité
/
Variation contingente négative
/
Endophénotypes
Type d'étude:
Etude diagnostique
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Psychiatry Investigation
Année:
2013
Type:
Article
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