An analysis on 200 randomized clinical isolates of Mycobacterium in Sichuan / 中华微生物学和免疫学杂志
Chinese Journal of Microbiology and Immunology
;
(12): 555-560, 2012.
Article
Dans Chinois
| WPRIM
| ID: wpr-429146
ABSTRACT
Objective To find out the resistant situation and drug of Mycobacteria patients in Sichuan and offer foundation for clinical.Methods Two hundred randomized clinical isolates of Mycobacterium were determined by Roche drug sensitivity and minimum inhibitory concentration (MIC) method.Results Of the 200 clinical isolates,192 stains were Mycobacterium tuberculosis(MTB) (96.0%),8 strains (4.0%) were non-tuberculosis mycobacterium(NTM).Of the 192 MTB strains,108( 57.3% ) sensitive strains and 84 (43.7%)stains were resistant to one or more than one drugs.Among these 84 resistant strains 23 were multi-drug resistant ( MDR,12.0% ),4 were extensively drug resistant( XDR,2.1% ).The anti-TB drug resistance rates wereSM(16.7%),INH(20.8%),RFP(17.2%),EMB(10.9%),PI(16.1%),LFX(8.8%),AMK ( 16.7% ),CPM ( 6.2% ),PTA ( 33.3% ),respectively.Conclusion The resistance rate of tuberculosis keeps at a high level in Sichuan,especially the resistance rate of multiple (≥4) drug,we should oar attention.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Type d'étude:
Essai clinique contrôlé
langue:
Chinois
Texte intégral:
Chinese Journal of Microbiology and Immunology
Année:
2012
Type:
Article
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