The applicated value of Gui piperazine strange maleate in the treatment of patients with acute cerebral infarction / 中国基层医药

ABSTRACT

Objective To explore the influence of Gui piperazine strange maleate on the high sensitive C-reactive protein(hs-CRP) and S100B in the serum of patients with acute cerebral infarction.Methods 90 patients with acute cerebral infarction were randomly divided into two groups,the control group(45 cases) and the treatment group (45 cases).The patients in the control group were treated through the conventional treatment,while the patients in the treatment group were treated plus Gui piperazine strange maleate.They were treated for fourteen days.The hs-CRP and S100B in the serum were detected before and after treatment.Results The total effective rates were 93.3％ in the treatment group and 84.4％ in the control group.There was a significant difference between two groups(x2 =4.0125,P ＜ 0.05).The hs-CRP and S100B were decreased after treatment in both groups (all P ＜ 0.05),and there was a significant difference between two groups after treatment (all P ＜ 0.05).Conclusion Gui piperazine strange maleate can improve acute cerebral infarction through mitigating inflammation.