Analysis of influecing factors of quality of life in rectal cancer patients with long-term survival / 中国肿瘤临床

ABSTRACT

Objective:To investigate the influencing factors of quality of life (QOL) in rectal cancer patients with long-term sur-vival (LTS). Methods:A total of 107 patients with stageⅡandⅢrectal cancers were enrolled in this study. Questionnaires were used to determine the clinical factors affecting the QOL of rectal cancer patients with LTS. Results:Physical, emotional, social, and sexual functions were better in patients without colostomy than in those who underwent surgery. However, bowel function was worse in pa-tients who did not undergo surgery (P<0.05). A decrease in social function and QOL was observed in patients who underwent more treatments, and fatigue and insomnia symptoms were more obvious (P<0.05). Logistic regression analysis indicated that treatment was an independent predictor of QOL and negatively correlated with QOL. Conclusion:Treatment is an independent predictor of QOL in patients with stageⅡandⅢrectal cancers, and is negatively correlated with QOL. Surgery is a major factor that affects patient QOL. Improvement of medical technology and reasonable chemoradiotherapy should ameliorate the QOL of patients with LTS.