A report of 18-month follow-up study on a case of classic maple syrup urine disease / 临床儿科杂志
Journal of Clinical Pediatrics
; (12): 968-971, 2013.
Article
de Zh
| WPRIM
| ID: wpr-441227
Bibliothèque responsable:
WPRO
ABSTRACT
Objectives To explore the long-term prognosis, treatment (especially dietary treatment) of classic maple syrup urine disease. Methods The complications and dietary treatment were observed by follow-up study of a classic MSUD patient. Results The patient have obvious damage in nervous system. However, reasonable dietary leucine tolerance therapy after the neonatal period can effectively reduce the metabolic crisis and complications. A mutation in BCKDHB gene was detected in the patient by genetic testing. Conclusion It is suggested that dietary restriction and monitoring of branched-chain amino acids are helpful to reduce the development of acute metabolic crisis and complications and improve the quality of life.
Texte intégral:
1
Indice:
WPRIM
Type d'étude:
Observational_studies
/
Prognostic_studies
langue:
Zh
Texte intégral:
Journal of Clinical Pediatrics
Année:
2013
Type:
Article