Analysis of the risk factors between anterior and posterior intracranial artery stenosis in acute stroke patients / 中国综合临床

ABSTRACT

Objective To investigate the association between vascular risk factors and the location of intracranial artery stenosis (anterior versus posterior).Methods Magnetic resonance angiography(MRA) were examined in 374 acute stroke patients.It was divided into two groups (anterior and posterior intracranial artery stenosis group).Analyzed possible risk factors.Results Univariate analysis showed there were differences between anterior and posterior intracranial artery stenosis in systolic blood pressure,history of smoking,drinking and stroke status,and national institutes of health stroke scale (NIHSS) score at discharge,short-term prognosis,serum creatinine,triglyceride,low density lipoprotein cholesterol (LDL-C) (P ＜ 0.05).In multivariate logistic regression analysis,high blood sugar (OR =1.135,95％ CI1.003-1.284),history of stroke(OR =1.133,95％ CI1.007-1.276),good short-term prognosis (OR =5.987,95％ CI1.441-24.873) were preferentially related to anterior intracranial artery stenosis,whereas history of smoking (OR =0.003,95 ％ CI0.000-0.376),high serum creatinine values (OR =0.509,95 ％ CI0.328-0.790),high triglyceride values (OR =0.054,95％ CI0.004-0.645) and high LDL-C values (OR =0.096,95％ CI0.015-0.608) were preferentially related to posterior intracranial artery stenosis.Conclusion Vascular risk factors appeared to exert different effects of risk for anterior and posterior intracranial artery stenosis.