Blonanserin-induced Mood Alteration in Schizophrenia and Schizoaffective Disorder: Two Cases
Clinical Psychopharmacology and Neuroscience
;
: 165-167, 2013.
Article
Dans Anglais
| WPRIM
| ID: wpr-44834
ABSTRACT
We report two outpatients, one with schizophrenia and one with schizoaffective disorder, who developed manic or hypomanic episodes following the initiation of blonanserin during the course of treatment. Blonanserin is a novel antipsychotic that acts as a 5-HT and D2 receptor antagonist. Both patients developed hypomanic episodes within 2 weeks of receiving a small dose (6-8 mg) of blonanserin, and one patient later developed full-blown mania; both episodes ended within 1 month of discontinuing blonanserin. The mood alteration observed in these cases suggests a possible antidepressant effect of blonanserin; thus, clinicians should monitor mood changes when administering this antipsychotic.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Patients en consultation externe
/
Troubles psychotiques
/
Schizophrénie
/
Neuroleptiques
/
Trouble bipolaire
/
Sérotonine
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Clinical Psychopharmacology and Neuroscience
Année:
2013
Type:
Article
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