Analysis of the risk factors of chronic kidney disease complicated with acute kidney injury / 中国基层医药

ABSTRACT

Objective To analyze the risk factors of chronic kidney disease complicated with acute kidney injury and its treatment efficacy.Methods 180 chronic kidney disease patients complicated with acute kidney injury were divided into the elderly group and the young group.The underlying diseases,risk factors of acute kidney injury and clinical efficacy were compared between the two groups.Results The proportions of chronic glomerulonephritis,nephrotic syndrome and lupus nephritis in young and middle-aged group were 37.8％,15.6％ and 20.0％,which were significantly higher than those in the elderly group (17.8％,8.9％,2.2％) (P ＜ 0.05).The proportions of diabetic nephropathy and hypertensive renal injury in elderly patients were 31.1％ and 24.4％,which were significantly higher than those in the young and middle-aged group (6.7％,4.4％) (P ＜ 0.05).In the old age group,the proportions of infections and renal toxicity drugs were 28.9％ and 22.2％,which were significantly higher than those in the young group.In the young and middle-aged group,the proportions of malignant hypertension and deterioration of the primary disease were 22.2％ and 26.7％,which were significantly higher than those in the elderly group (P ＜0.05).The total effective rate of the young group was 88.9％,which was significantly higher than 71.1％ of the elderly group (x2 =6.846,P ＜ 0.05).Conclusion Elderly and young and middle-aged chronic kidney disease patients complicated with acute kidney injury have differences in risk factors and clinical efficacy.