Matrine and anti-tumor drugs in inhibiting the growth of human lung cancer cell line / 中西医结合学报
Journal of Integrative Medicine
; (12): 163-5, 2008.
Article
Dans Zh
| WPRIM
| ID: wpr-449429
Responsable en Bibliothèque :
WPRO
ABSTRACT
OBJECTIVE: To study the activities of matrine and anti-tumor drugs on SPCA/I human lung adenocarcinoma cell line. METHODS: Suppression effects of different concentrations of matrine and matrine combined with anti-tumor drugs on lung cancer cells were measured by methyl thiazolyl tetrazolium (MTT) colorimetric assay. RESULTS: Different concentrations of matrine could inhibit the growth of SPCA/I human lung adenocarcinoma cells and there was a positive correlation between the inhibition rate and the drug concentration. Different concentrations of matrine combined with anti-tumor drugs had higher growth inhibition rate than anti-tumor drugs alone. CONCLUSION: Matrine has direct growth suppression effect on SPCA/I human lung adenocarcinoma cells and matrine combined with anti-tumor drugs shows a significant synergistic effect on tumor cells.
Texte intégral:
1
Indice:
WPRIM
langue:
Zh
Texte intégral:
Journal of Integrative Medicine
Année:
2008
Type:
Article