Clinical effectiveness study of laparoscopic and open radical gastrectomy for gastric cancer patients / 中国医师进修杂志

ABSTRACT

Objective To investigate the clinical effectiveness of laparoscopic and open radical gastrectomy for gastric cancer patients.Methods Seventy-two gastric cancer patients who underwent laparoscopic or open radical gastrectomy were enrolled in this study.Laparoscopic radical gastrectomy group had 38 cases,open radical gastrectomy group had 32 cases.The operating time,length of incision,bleeding volume during operation,postoperative hospital stay and the level of C reactive protein were compared.Results All patients were performed operation successfully.No patient transferred open operation in laparoscopic radical gastrectomy group.No death because of operation.The patients in laparoscopic radical gastrectomy group took longer operating time,but shorter length of incision,less bleeding volume during operation,there was significant difference (P ＜ 0.05).But the number of clearing lymph nodes between two groups had no significant difference (P ＞ 0.05).Compared with open radical gastrectomy group,the patients in laparoscopic radical gastrectomy group had shorter exhaust time,early out-of-bed activity,shorter postoperative hospital stay,lower rate of complication,there was significant difference (P ＜ 0.05).The level of C reactive protein before operation had no significant difference between two groups (P ＞ 0.05),and level of C reactive protein had the tendency of improve previously and decrease lately.The level of C reactive protein in laparoscopic radical gastrectomy group was significantly lower than that in open radical gastrectomy group at the postoperative 1st,3rd,5th day[(9.33 ± 0.27) mg/L vs.(11.29 ± 0.42) mg/L,(7.16 ± 0.18) mg/L vs.(9.87±0.65) mg/L,(4.38 ±0.41) mg/Lvs.(6.97±0.51) mg/L](P＜0.05).Conclusion Laparoscopic radical gastrectomy is useful in treating gastric cancer for it's advantage of better security,better effectiveness,quicker recover and less trauma.