C-Kit-Negative Gastrointestinal Stromal Tumor in the Stomach
Journal of Gastric Cancer
;
: 290-294, 2015.
Article
Dans Anglais
| WPRIM
| ID: wpr-45379
ABSTRACT
C-kit-negative gastrointestinal stromal tumors (GISTs) are uncommon, and there have been few reports about the diagnosis and treatment of c-kit-negative GISTs in the stomach. We report the case of a patient who was diagnosed with a huge and atypical GIST in the stomach. The GIST was completely resected and finally diagnosed as c-kit-negative GIST based on immunohistochemical staining of tumor cells, which were negative for CD117 and CD34 and positive for Discovered on GIST-1 (DOG1). C-kit-negative GISTs could be treated by complete resection and/or imatinib, which is the same treatment for c-kit-positive GISTs.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Estomac
/
Protéines proto-oncogènes c-kit
/
Tumeurs stromales gastro-intestinales
/
Diagnostic
/
Mésilate d'imatinib
Type d'étude:
Etude diagnostique
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Journal of Gastric Cancer
Année:
2015
Type:
Article
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