Screening Technology for Traditional Chinese Medicine New Drug and Practice / 世界科学技术-中医药现代化
World Science and Technology-Modernization of Traditional Chinese Medicine
; (12): 1696-1702, 2014.
Article
de Zh
| WPRIM
| ID: wpr-453934
Bibliothèque responsable:
WPRO
ABSTRACT
This article focused on summarization of the available new screening technology for traditional Chinese medicine (TCM) new drug, including high throughput screening (HTS), biological chip, molecular biological chro-matography, high content screening (HCS), network pharmacology, proteomics, and computer-aided drug design (CADD). And in this review, one example that we applied CADD technology (such as molecular docking, pharma-cophore and molecular similarity) in lipid-lowering TCM new drug development was given. Based on the mechanism of lipid metabolism, CADD technology provided a good method on the prescription optimization and mechanism study. In addition, TCM new drug development proposal which displayed in this paper may provide a useful strategy for screening of TCM new drug.
Texte intégral:
1
Indice:
WPRIM
Type d'étude:
Diagnostic_studies
/
Screening_studies
langue:
Zh
Texte intégral:
World Science and Technology-Modernization of Traditional Chinese Medicine
Année:
2014
Type:
Article