Histological observation of rat's parotid gland after ligation and reopening of the main duct / 实用口腔医学杂志

ABSTRACT

Objective:To investigate the histological changes of parotid gland after ligation and reopening of the main duct.Meth-odsThe right parotid main duct was ligated for 14 days and then reopened,the specimen were harvested at day 0,1,3,5,7,10,14 and 21 after reopening(n=5 )respectively.By HE staining and Morphology measurement,the morphological and volume fraction changes of acinus,duct and mesenchyma were observed and measured.Results:The parotid gland atrophied significantly 14 days af-ter the duct ligation.From day 3 after duct reopening,the acinar volume fraction continued to increase,both the duct and the mesen-chymal tissue volume fraction continued to decrease significantly(P0.05).Conclu-sionAfter reopening of the ligated main duct the atrophied parotid gland is able to regenerate to be normal.