Your browser doesn't support javascript.
loading
Relationship between adiponectin -11,377C > G Gene polymorphism and risk of coronary heart disease / 实用医学杂志
The Journal of Practical Medicine ; (24): 2405-2407, 2014.
Article Dans Chinois | WPRIM | ID: wpr-455195
ABSTRACT
Objective To investigate the relationship between the polymorphism of adiponectin -11 ,377C> G gene and the risk of coronary heart disease(CHD). Methods A total of 126 CHD patients and 130 healthy controls were enrolled and the frequency of each genotypes and allele gene of adiponectin -11 ,377C > G were detected by polymerase chain reaction fragment length polymorphism (PCR-RFLP). Results (1) The adiponectin gene -11,377C > G sites existed gene polymorphism and the three genotypes were GG, CG and CC. (2) There was statistical difference between CHD group and control group; The G allele frequency of CHD group was significantly higher than that in control group (P G between acute coronary syndrome (ACS) group and stable angina group . ( 4 ) The risk of CHD were increased in CHD patients with G allele gene of adiponectin-11,377C > G (P G is associated with the increased risk of CHD. The increased G allele gene frequency may represent the increased risk of CHD.

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Type d'étude: Etude d'étiologie / Facteurs de risque langue: Chinois Texte intégral: The Journal of Practical Medicine Année: 2014 Type: Article

Documents relatifs à ce sujet

MEDLINE

...
LILACS

LIS

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) Type d'étude: Etude d'étiologie / Facteurs de risque langue: Chinois Texte intégral: The Journal of Practical Medicine Année: 2014 Type: Article