Two Cases of Hepatoma with Cutaneous Metastases / 대한피부과학회지

ABSTRACT

Skin metastases from internal cancers are unusual; from a hepatoma they are extremely rare. The most common clinical presentation are solitary or multiple nodules that have appeared in one area of the body. Other forms include inflammatory and sclerodermoid metastatic growths. Case one was a 54-year-old male who had had partial hepatectomy of the right lobe of his liver following diagnosis of hepatocellular carcinoma five years ago. He presented with a 10 month history of a solitary nodule on the chin. Another case was a 46-year-old male, who had developed hepatocellular carcinoma forming a large subcutaneous mass by hemat,ogenous metastasis of the left zygomatic bone, masseter muscle and subcutaneous fat. Additional metastases were observed in the portal vein and multiple bones including the right shoulder, the 1st, 2nd, 3rd sacral spine and the right 3rd, 7th rib. In view of the clinical and histopathologic findings both skin tumors were considered to originate from the liver. The skin metastases may be indicative of progression by the primary tumor and also the first indication that a malignant tumor has not been eradicated.