Effect of Mometasone Furoate Nasal Sprays Combined with Montelukast on Allergic Rhinitis / 中国药师

ABSTRACT

Objective: To observe the curative effect and reoccurrence prevention of mometasone furoate nasal sprays combined with montelukast on allergic rhinitis ( AR) . Methods:Totally 74 cases of patients with AR were divided into the observation group and the control at random. The patients in the observation group were given mometasone furoate nasal sprays combined with montelukast, while the patients in the control group were only given mometasone furoate nasal sprays for 4 weeks. The clinical curative effect and ad-verse drug reaction ( ADR) in the two groups were observed and compared, and the reoccurrence rates in the two groups after one-year following-up were compared as well. Results:The total efficiency in the observation group was 94. 59%, which was much higher than that in the control group (78. 38%), and the reoccurrence rate in one year was 22. 86% in the observation group, which was much lower than that in the control group (48. 28%) with statistical differences (P0.05). Conclusion: Compared with mometasone furoate nasal sprays, the application of mometasone furoate nasal sprays combined with montelukast in the treatment of AR can reduce the reoccur-rence rate with good security.