Obesity and insulin resistance in apparently healthy Korean men / 대한내과학회지
Korean Journal of Medicine
;
: 451-457, 2003.
Article
Dans Coréen
| WPRIM
| ID: wpr-46041
ABSTRACT
BACKGROUND:
Several reports document Asians have a strong tendency of developing insulin resistance. We aimed to evaluate the relative effects of insulin resistance and obesity on coronary heart disease (CHD) risk factors and to clarify whether insulin resistance accentuates the effect of obesity on CHD risk factors in apparently healthy men.METHODS:
We conducted the cross-sectional survey of 4,067 apparently healthy Korean men aged 20-83 years, with a body mass index (BMI) ranging from 15.19 to 40.29 kgm-2. Insulin resistance was defined as the highest decile of homeostasis model assessment (HOMA-IR) in the lean group (BMI<23 kgm-2; 1,438 subjects).RESULTS:
The prevalence of insulin resistance was 24.7% in the overweight subgroup (23CONCLUSION:
WC is closely associated with non-traditional markers for CHD, such as raised Apo B, hypertriglyceridaemia, and TC/HDL ratio predicting small, dense LDL particles. Insulin resistance in the obese men is more prevalent than would be expected and accentuates the effect of obesity on CHD risk factors.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Apolipoprotéines
/
Apolipoprotéines B
/
Triglycéride
/
Glycémie
/
Pression sanguine
/
Protéine C-réactive
/
Insulinorésistance
/
Indice de masse corporelle
/
Cholestérol
/
Prévalence
Type d'étude:
Etude d'étiologie
/
Étude observationnelle
/
Étude de prévalence
/
Étude pronostique
Limites du sujet:
Humains
/
Mâle
langue:
Coréen
Texte intégral:
Korean Journal of Medicine
Année:
2003
Type:
Article
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