B cell line epitopes prediction of human cytomegalovirus glycoprotein B / 军事医学
Military Medical Sciences
; (12): 184-188, 2015.
Article
de Zh
| WPRIM
| ID: wpr-460728
Bibliothèque responsable:
WPRO
ABSTRACT
Objective To predict the B cell line epitopes of human cytomegalovirus glycoprotein (gB)by analyzing its structure and physicochemical properties using bioinformatics approaches .Methods Based on the sequence of the HCMV gB,the probable B cell epitopes are predicted using two online prediction programs and DNAstar software .Meanwhile,the tertiary structure of gB was constructed by homologous modeling with the assistance of SWISS -MODEL server to rule out im-possible B cell epitopes .Results and Conclusion The B cell line epitopes of gB are predicted , which provides a theoreti-cal basis for further verification of gB immunodominant epitopes and screening the source plasma with high HCMV IgG titer .
Texte intégral:
1
Indice:
WPRIM
Type d'étude:
Prognostic_studies
langue:
Zh
Texte intégral:
Military Medical Sciences
Année:
2015
Type:
Article