Effect of mlodipine/hydrochlorothiazide in patients with essential hypertension:A systematic review / 重庆医学
Chongqing Medicine
;
(36): 673-675, 2015.
Article
Dans Chinois
| WPRIM
| ID: wpr-462310
ABSTRACT
Objective To systematically evaluate the efficacy and safety of amlodipine (A)/hydrochlorothiazide(H) versus val‐sartan(V)/hydrochlorothiazide(H) in treatment of essential hypertension .Methods Literature was retrieved online in Cochrane Li‐brary ,PubMed ,OVID ,MEDLINE ,EMBASE ,CBM ,CNKI ,VIP and Wan fang database up to November 2013 .Relevant magazines were retrieved manually .Quality of the included studies was assessed and Meta‐analysis was performed with RevMan 5 .2 software . Results Seven randomized controlled trials(RCTs) were finally included .Meta‐analyses showed thatin terms of lowering ABP ,V/H group was more effective than A/H group ,the difference was statistically significant (P0 .05) .Ad‐verse events occurred less frequently with V/H group compared with A/H group ,the difference was statistically significant (P<0 .05) .Conclusion A/H treatment of essential hypertension is inferior to V/H ,and has more adverse events .
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Type d'étude:
Essai clinique contrôlé
/
Revues systématiques évaluées
langue:
Chinois
Texte intégral:
Chongqing Medicine
Année:
2015
Type:
Article
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