Uniformity Study of Felodipine Sustained-release Tablets by NIRS / 中国药师
China Pharmacist
;
(12): 753-755, 2015.
Article
Dans Chinois
| WPRIM
| ID: wpr-464124
ABSTRACT
Objective:
To develop the uniformity models for felodipine sustalned-release tablets from 3 manufacturers by NIRS in order to study the difference in the preparation technology and detect and screen the tablets quickly by the robust, accurate and repre-sentative models.Methods:
The uniformity models for the tablets from 3 manufacturers among 6 manufacturers with evaluative casual inspection were established by NIRS. Region 4 000-9 000 cm-1 was chosen as the modeling section, and the first derivative plus vector normalization was used as the preprocessing method.Results:
The uniformity models for the tablets from the three manufacturers was established and used to predict the samplings from the six manufacturers. The prediction success rate was 100%.Conclusion:
NIRS can be used to identify felodipine sustalned-release tablets from different manufacturers quickly and study the preparation technology.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Type d'étude:
Étude pronostique
langue:
Chinois
Texte intégral:
China Pharmacist
Année:
2015
Type:
Article
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