The comparative analysis and bias evaluation on the results of serum CK,AST and LDH between two different kinds of biochemical analysis system / 国际检验医学杂志

ABSTRACT

Objective To discuss the comparability and bias evaluation on the results of serum creatine kinase (CK ) ,aspartate aminotransferase (AST) ,lactate dehydrogenase (LDH) inspection results between the two different kinds of biochemical analysis system .Methods The control quality materials with two concentration were detected respectively for degree of precision ,and the assessment standard was from manufacturer introductions and laboratory setting .Then in accordance with American Clinical and Laboratory Standard Institute(CLSI) document EP9‐A2 ,100 patients serum CK、AST、LDH were detected .Afterwards the relative bias(SE% ) was calculated ,and the comparative analysis bias evaluation was judged according to the half of CLIA′88 allowed total error .Results The variable coefficients mainly conformed to the requirements ,and the experimental results were reliable .The oth‐ers mainly lower than the acceptable limit besides SE% for LDH higher than it .Conclusion It is necessary to execute comparative analysis and bias evaluation to ensure the accuracy and comparability if the same item is detected in two analysis system .