Comparison of the effects of dezocine and tramadol for the prevention of shivering in cesarean section / 中国基层医药

ABSTRACT

Objective To observe the effect and safety of dezocine and tramadol for the prevention of shive-ring in cesarean section.Methods According to the digital table,240 routine cesarean mothers (both epidural anesthesia,ASA Ⅰ-Ⅱ)were randomly divided into three groups,each group in 80 cases.After the completion of combined spinal epidural,group A received verdict preventive maternal supine dezocine intravenous 0.1 mg/kg(dilu-ted to 20mL with saline),group B for prophylactic intravenous tramadol 1 mg/kg(with saline diluted to 20mL),group C(control group)received normal saline 20mL,continuous monitoring of perioperative respiratory,circulation chan-ges,maternal chills,adverse reactions and Apgar score were observed and recorded.Results The incidence of post-anesthetic shivering maternal of group A and group B were 5.0%,7.5% respectively,while the rate was 60% in group C,there was significant difference between group A and group B(H=3.418,P=0.019);,but the maternal nausea and vomiting incidence of group B(45.0%)was significantly higher than those of group A(10.0%)and group C(7.5%)(χ2 =11.491,P=0.021).There were no statistically significant differences in neonatal Apgar score among three groups(F=10.062,P=0.017).Conclusion Tramadol and dezocine can effectively prevent shivering during cesarean section and had no effect on the Apgar score,but tramadol incidence of nausea and vomiting was sig-nificantly higher than that of Dezocine,which is recommended for clinical use to rank and file Sim prevent cesarean section shivering response.