Biocompatibility of carbon fiber interbody fusion cage versus titanium mesh cage in treatment of lumbar disc degeneration / 中国组织工程研究

ABSTRACT

BACKGROUND:The endplate can be combined closely with different intervertebral fusion cages through the pedicle screw internal fixation system, to provide a more reliable spine stability for reconstruction of intervertebral height, lumbar physiological curvature and biomechanical function. OBJECTIVE:To compare the effectiveness of carbon fiber interbody fusion cage and titanium mesh cage in lumbar disc degeneration. METHODS:Sixty patients with L3-S1 RESULTS AND CONCLUSION: Sixty patients completed the 3-27 months folow-up, and had good bone fusion. Lumbar activity was normal in al the patients at 3 months after treatment. The Japanese Orthopaedic Association Scores at 3 months after implantation and the intervertebral height at 1 week after implantation were significantly improved in the two groups (P < 0.05), but there was no difference between the two groups. The materials in the lumbar disc degeneration who underwent posterior lumbar interbody fusion, 33 males and 27 females, were randomized into carbon fiber interbody fusion cage group and titanium mesh cage group. Japanese Orthopaedic Association Scores were compared between the two groups before and after the implantation, as wel as the intervertebral height, intervertebral fusion and complications. two groups had good biocompatibility with no rejection and no infection. Fusion cage subsidence occurred in two cases from the titanium mesh cage group. These findings indicate that both of carbon fiber interbody fusion cage and titanium mesh cage have good biocompatibility, improve the stability of the vertebral body, and restore the intervertebral height. Moreover, the carbon fiber material performance is better than the metal titanium mesh because of lower complication rate.