The clinical observation of carboprost methylate suppositorites combined with oxytocin in the prevention of postpartum hemorrhage in patients of caesarean section with scarred uterus / 中国基层医药

ABSTRACT

Objective To explore the effect and application value of carboprost methylate suppositorites combined with oxytocin in preventing scar uterus bleeding of patients with cesarean section surgery.Methods According to the digital table,100 patients received cesarean section with scarred uterus were randomly divided into the observation group and control group.The control group was given oxytocin,the observation group received carboprost methylate suppositorites combined with oxytocin.The bleeding in the two groups was observed.Results In the observation group,postpartum hemorrhage occurred in 1 case,2h postpartum haemorrhage amount was (120.73 ±45.28)mL,24h postpartum haemorrhage amount was (283.32 ± 56.78)mL,compared with the control group,the postpartum hemorrhage rate decreased,postpartum 2h,24h blood loss decreased,the differences were statistically significant (x2 =4.891,t =6.582,7.351,all P ＜ 0.05).In the observation group,4 cases occurred nausea and vomiting,13 cases of diarrhea,high blood pressure in 7 cases,facial flush in 1 case,compared with the control group,there were no statistically significant differences in the incidence rates of adverse reactions (x2 =0.153,0.053,0.919,1.041,all P ＞0.05).Conclusion Application of carboprost methylate suppositorites combined with oxytocin in scar uterus patients with cesarean section can reduce postpartum blood loss in the operation,reduce the incidence of postpartum hemorrhage,and not increase adverse reactions.