Effect of calcitriol on subclinical macrovascular disease in type 2 diabetic patients / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
; (12): 251-253, 2015.
Article
Dans Zh
| WPRIM
| ID: wpr-468509
Responsable en Bibliothèque :
WPRO
ABSTRACT
The changes of carotid intima media thickness (cIMT) in type 2 diabetic patients with vitamin D insufficiency and subclinical macrovascular disease after 12 months' intervention therapy with calcitriol were observed.86 patients with vitamin D insufficiency [25 (OH) D<30 ng/ml] and subclinical macrovascular disease were randomized to group A (n =44,treated with 0.5 μg/day calcitriol) or group B (n =42,blank control) for 12 months.40 patients in each group completed the follow up.After 12 months of therapy with calcitriol (0.5 μg.qd.po.),levels of high sensitive-Creactive protein,sCD36,and cIMT were significantly decreased,while 25 (OH) D and ankle brachial index were significantly increased (P<0.05) in group A,suggesting that calcitriol could improve cIMT in patients with vitamin D insufficiency and subclinical macrovascular disease.
Texte intégral:
1
Indice:
WPRIM
Type d'étude:
Clinical_trials
langue:
Zh
Texte intégral:
Chinese Journal of Endocrinology and Metabolism
Année:
2015
Type:
Article