Risk factors related to early survival after lung transplantation for idiopathic pulmonary fibrosis / 中华器官移植杂志

ABSTRACT

Objective To estimate the effects of risk factors on early survuval (90 days) after lung transplantation for idiopathic pulmonary fibrosis (IPF).Method We reviewed 49 cases of lung tansplant male patients which suffered from IPF.Two groups were set up according to the early survival.The early outcomes (90 days) were compared between two groups by multiple logistic regression analysis.Result The early survival rate was 81.6％.Multivariate analysis confirmed that mean pulmonary artery pressure and bilateral lung transplantation (BLTx) were risk factors after adjustment for potential confounders.Recipients' age,lung volume reduction on donors,and use of extracorporeal membrane oxygenation (ECMO) were not risk factors for early mortality.Conclusion The increased pulmonary artery pressure and BLTx are risk factors for death after lung transplantation in IPF.Preoperative evaluation of mean pulmonary artery pressure and choosing suitable operative method could improve the surgical outcomes of lung transplantation.