Effects Of Chitosan On Human Osteoblasts
Journal of the Korean Association of Oral and Maxillofacial Surgeons
;
: 280-285, 2002.
Article
Dans Coréen
| WPRIM
| ID: wpr-46968
ABSTRACT
As the result of the study concerning "bone inducibility of chitosan", 1. "BMP-2"was observed mainly through the test when the "osteoblast"is exposed to the "chitosan". The expression of BMP-2 was 542.63 times compared to control after 2 hours exposure and it was maintained 16.60 times till 24 hours. 2. The expression of BMP-4 was decreased compared to control during exposure. 3. The expression of BMP-7 revealed two peaks during exposure. 4. The expression of osteocalcin was increased in early phase, and then decreased. Although it is not clear whether the "chitosan"is clinically effective material as a "bone induction material", we could say that it has a function for bone induction. Further detailed study will be required.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Ostéoblastes
/
Ostéocalcine
/
Chitosane
/
Protéine morphogénétique osseuse de type 7
Limites du sujet:
Humains
langue:
Coréen
Texte intégral:
Journal of the Korean Association of Oral and Maxillofacial Surgeons
Année:
2002
Type:
Article
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