Research progress of alogliptin in treatment of type 2 diabetes mellitus / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism
;
(12): 868-871, 2014.
Article
Dans Chinois
| WPRIM
| ID: wpr-469932
ABSTRACT
Alogliptin is a novel dipeptide peptidase-4 inhibitor approved for the treatment of type 2 diabetic mellitus.Numerous clinical studies showed that alogliptin alone or in combination with other oral antidiabetic drugs or insulin can substantially control the level of plasma glucose and glycated hemoglobin (HbA1c) in type 2 diabetic patients.12.5 to 25 mg alogliptin alone once daily reduced HbA1c by 0.56% to 0.59% ; while combination with other antidiabetic agents resulted additional HbA1c lowering of 0.4% to 0.8%.Alogliptin was well tolerated,with low incidence of hypoglycemia and no weight gain.Furthermore,alogliptin displayed no extra cardiovascular risk in patients with cardiovascular diseases.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Chinese Journal of Endocrinology and Metabolism
Année:
2014
Type:
Article
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