Corelation between the Finding of Magnifying Endoscopy and Histologic Finding in the Helicobactor Pylori Induced Gastritis / 대한소화기내시경학회지

ABSTRACT

BACKGROUND/AIMS: This is the study to find diagnostic possibility of the H. pylori induced gastritis by using the magnifying endoscope. METHODS: The objectives were 144 pathologies from 48 patients with gastritis. The three sites of gastric mucosa have been magnified up to 80 times by using the magnifying endoscope. According to the patterns of the collecting venule, they have been classified into 3 patterns; regular (R), irregular (I) and disappearance (D) pattern and biopsy of each part has been performed. Each tissue has been evaluated into five kinds of morphological index (point 0~3) by using an updated Sydney system. RESULTS: In 144 collecting venule, R, I and D-pattern was 19, 67, 58, respectively. Regarding the total score of morphologic points, the point of R-pattern was less than that of D-pattern (p<0.05). Regarding the infection of H. pyrori, the infection rate was 0%, 53.7%, and 60.3% in each pattern, and infection rate of R-pattern was less than other two patterns (p<0.05). Regarding the activity of neutrophile, R-pattern was less than those of I and D-pattern (p<0.05). CONCLUSIONS: Observance of the collecting venule of the gastric mucosa by magnifying endoscopy is considered to be useful when estimating the inflammation degree and H. pylori infection.