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Effect of Pricking Blood Therapy on Behavior and Gene Expression in a Rat Model of Migraine / 针灸推拿医学(英文版)
Journal of Acupuncture and Tuina Science ; (6): 335-338, 2009.
Article Dans Chinois | WPRIM | ID: wpr-474366
ABSTRACT

Objective:

To investigate the effect of pricking blood therapy on behavior and brainstem c-fos and c-jun gene expression in migraine rats.

Methods:

A rat model of migraine was made with nitroglycerol. The rats were treated by pricking blood. Rat behavior was observed. Brainstem c-fos and c-jun gene expression was examined by immunohistochemistry.

Results:

Ear redness improved significantly, the number of head scratchings decreased obviously (P<0.05) and c-fos and c-jun expression was reduced markedly (P<0.01) in the treatment group after pricking blood compared with the model group and the blank group.

Conclusion:

Pricking blood treatment can improve behavior indices and reduce c-fos and c-jun positive expression in migraine rats.

Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) langue: Chinois Texte intégral: Journal of Acupuncture and Tuina Science Année: 2009 Type: Article

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Texte intégral: Disponible Indice: WPRIM (Pacifique occidental) langue: Chinois Texte intégral: Journal of Acupuncture and Tuina Science Année: 2009 Type: Article