Emerging role of high mobility group protein B1 in pulmonary fibrosis / 医学研究生学报
Journal of Medical Postgraduates
; (12): 875-879, 2015.
Article
Dans Zh
| WPRIM
| ID: wpr-476167
Responsable en Bibliothèque :
WPRO
ABSTRACT
Pulmonary fibrosis , an important cause of pulmonary diseases , has no effective protective and therapeutic meas-ures.Recent studies showed high mobility group protein B 1 (HMGB1) has an important role in the development of pulmonary fibrosis and many HMGB1 antagonists can alleviate pulmonary fibrosis in animal models .This paper summarizes the structure , function, intra-cellular signal transduction of HMGB1, the expression change of HMGB1 in pulmonary fibrosis and HMGB1 targeted therapy in pulmo-nary fibrosis in order to provide an effective basis for clinical treatment of pulmonary fibrosis .
Texte intégral:
1
Indice:
WPRIM
langue:
Zh
Texte intégral:
Journal of Medical Postgraduates
Année:
2015
Type:
Article