MRI findings of intracranial venous sinus thrombosis and brain parenchymal lesions / 中国脑血管病杂志

ABSTRACT

Objective To investigate the findings and prognosis of head MRI and brain parenchymal lesions in patients with intracranial venous sinus thrombosis. Methods The clinical manifestations and imaging data of 41 patients with intracranial venous sinus thrombosis were analyzed retrospectively. According to the head MRI,the patients were divided into a brain parenchymal lesion positive group (n = 21)and a negative group (n =20). The clinical manifestations and the difference of the affected venous sinus in patients of both groups were analyzed. Results The proportion of dehydration,epilepsy,motor disorders,and psychiatric symptoms in the positive group were 28.6% (n =6)vs. 0% (n =0),57. 1% (n =12)vs. 15. 0%(n = 3),47. 6% (n = 10)vs. 5. 0% (n = 1),and 33. 3% (n = 7)vs. 5. 0% (n = 1),respectively. There were significant differences (all P < 0. 05). The proportion of the occurrence of superior sagittal sinus thrombosis in the positive group was lower than that in the negative group (47. 6% [n = 10]vs. 80. 0%[n = 16];P = 0. 031). At discharge,the proportion of complete recovery (modified Rankin score 0 -1)in the positive group was lower than that in the negative group (71. 4% [n = 15]vs. 100% [n = 20];P =0. 032). Conclusion Compare with the clinical symptoms of the positive patients,the patients with intracranial venous sinus thrombosis and those with negative brain parenchymal lesions are relatively minor,their prognoses are better,and the thrombi are more involved in superior sagittal sinus.