Predictive value of detection of serum Cys -C and hs -CRP in cardiovascular adverse events in patients with primary hypertension / 中国基层医药

ABSTRACT

Objective To explore the predictive value of detection of serum Cys -C and hs -CRP in cardio-vascular adverse events of patients with primary hypertension.Methods 138 patients with hypertension were selected and their serum Cys -C and hs -CRP levels were detected.Patients were given conventional treatment and blood pressure was controlled stably.Two years later,patients were divided into stable group(96 cases)and progression group(42 cases)according to the occurrence of cardiovascular adverse events,additionally,42 people received physi-cal examination in corresponding period were selected as control group.The levels of serum Cys -C and hs -CRP were detected again.The detection results and complications were analyzed retrospectively.Results For initial detec-tion,the levels of serum Cys -C[(0.87 ±0.39)mg/L,(1.16 ±0.47)mg/L]and hs -CRP[(1.79 ±0.56)mg/L, (2.26 ±0.91)mg/L]in the stable and progression groups were higher than the control group[(0.59 ±0.32)mg/L, (0.68 ±0.37)mg/L],and those in the progression group were higher than the stable group(t =2.162,3.904, 5.237,6.441,all P 0.05),but the levels in the progression group increased obviously(t =2.146,3.144,all P <0.01).Conclusion The levels of serum Cys -C and hs -CRP were closely related to disease progression and prognosis.And the detection of them can predict the progression of disease,conductive to taking intervening measures for the early stage.