Current research of the role of Sox2 in Glioblastoma Multiforme / 天津医药
Tianjin Medical Journal
;
(12): 1467-1469, 2015.
Article
Dans Chinois
| WPRIM
| ID: wpr-484695
ABSTRACT
Glioblastoma (GBM) is one of the WHO gradeⅣmalignancies, which is an acentral nervous system cancer with poor prognosis unless the lesion is in the brain stem. The incidence of GBM accounts for 80%of human primary malignant tumors in brain. Only 5%GBM can survive up to 5-years. Many researches showed that Sox2 is a pluripotent regulator, and muta?tion or abnormal function of Sox2 are closely related to the development of GBM. There are studies demonstrated the possibil?ity of using Sox2 gene as apotential target for GBM therapy. This paper reviewed recent progress in GBM.
Texte intégral:
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Indice:
WPRIM (Pacifique occidental)
langue:
Chinois
Texte intégral:
Tianjin Medical Journal
Année:
2015
Type:
Article
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