Surfactant protein C gene mutations associated with children interstitial lung disease / 国际儿科学杂志

ABSTRACT

Surfactant protein C(SP-C)is found to be expressed only in the alveolar type Ⅱ cells(AECⅡ),surfactant protein C gene mutations are found to be associated with Children interstitial lung disease.This review discusses the mechanism,diagnosis and therapy of the interstitial lung disease induced by the surfactant protein C gene mutations.