Clinical Course of Segmental Vitiligo: A Retrospective Study of Eighty-Seven Patients
Annals of Dermatology
;
: 61-65, 2014.
Article
Dans Anglais
| WPRIM
| ID: wpr-48645
ABSTRACT
BACKGROUND:
Vitiligo is an acquired disorder characterized by a progressive loss of melanocytes, which is difficult to manage and has an unknown prognosis. The subtype of segmental vitiligo (SV) has been established but it has not been adequately characterized.OBJECTIVE:
To collect long-term follow-up data for evaluating the clinical course of SV.METHODS:
This study included 87 patients who were diagnosed with SV and were monitored at a clinic. Patients were classified into the following three groups according to disease activity.RESULTS:
Among the patients with SV, 63.2% had stable disease, 14.9% had disease recurrence between two and four years after disease onset, and 21.8% had disease recurrence at four or more than four years after disease onset. Among the 44 patients (50.2%) who were monitored continuously over a four-year period, 19 (43.2%) experienced a recurrence at four or more than four years after disease onset.CONCLUSION:
Our results suggest that, contrary to previous reports, some patients with SV may not experience disease stability over an extended period of time. Disease recurrence can occur after years of stability, and we propose that long-term follow-up data can be used to characterize SV. This information about the clinical course of SV has implications for treatment and prognosis.
Texte intégral:
Disponible
Indice:
WPRIM (Pacifique occidental)
Sujet Principal:
Pronostic
/
Récidive
/
Vitiligo
/
Études rétrospectives
/
Études de suivi
/
Mélanocytes
Type d'étude:
Étude observationnelle
/
Étude pronostique
Limites du sujet:
Humains
langue:
Anglais
Texte intégral:
Annals of Dermatology
Année:
2014
Type:
Article
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