Clinical Effects of Gamma Globulin at Different Doses Combined with Dexamethasone in the Treatment of Children with Severe Idiopathic Thrombocytopenic Purpura / 中国药师
China Pharmacist
; (12): 538-540, 2016.
Article
de Zh
| WPRIM
| ID: wpr-487727
Bibliothèque responsable:
WPRO
ABSTRACT
Objective:To explore the efficacy of gamma globulin at different doses combined with dexamethasone in the treatment of children with severe idiopathic thrombocytopenic purpura. Methods: Totally 96 cases of patients with idiopathic thrombocytopenic purpura were divided into group A ( standard high dose of gamma globulin+dexamethasone) , group B ( middle dose of gamma globulin+dexamethasone) and the control group ( dexamethasone) . The clinical effects and platelet parameters of the three groups were com-pared. Results:The levels of PLT, PCT and PDW in group A and group B after the treatment were higher than those in the control group(P0. 05). The clinical effective rate of group A and group B was higher than that in the control group(P0.05). There was no significant difference in the incidence of adverse reactions among the three groups (P>0. 05). Conclusion:Gamma globulin at middle dose shows significant effect as at high dose in the patients with ITP, which can reduce the dosage and is worthy of clinical promotion.
Texte intégral:
1
Indice:
WPRIM
langue:
Zh
Texte intégral:
China Pharmacist
Année:
2016
Type:
Article