Potassium-Titanyl-Phosphate Laser Photoselective Vaporization of the Prostate in Patients with Benign Prostatic Hyperplasia with Detrusor Underactivity: Influence on Detrusor Pressure

ABSTRACT

PURPOSE: Potassium-titanyl-phosphate laser photoselective vaporization of the prostate (PVP) is a safe and effective treatment for patients with symptomatic benign prostatic hyperplasia (BPH). The aim of this study was to assess the influence and the effect of PVP in BPH patients with detrusor underactivity. MATERIALS AND METHODS: We evaluated 21 patients with detrusor under-activity treated with PVP for BPH from January 2006 to December 2007. Detrusor underactivity was defined as detrusor pressure at maximal flow rate (Qmax) of less than 30 cmH2O and Qmax of less than 15 ml/s. Urodynamic studies were performed and international prostate symptom score (IPSS) and quality of life (QoL) scores were assessed preoperatively and at 6 months postoperatively. RESULTS: There were significant improvements in Qmax, voiding urine volume, post-void residual urine volume, IPSS, and QoL scores at 6 months after PVP treatment. However, patients did not show significant changes in maximal bladder capacity, bladder compliance, or detrusor pressure at Qmax. CONCLUSIONS: Even though BPH patients had detrusor underactivity, PVP was an effective surgical procedure. However, PVP did not make any significant difference on detrusor pressure at Qmax in 6 months.